4th Braunschweig International Symposium on Pharmaceutical Engineering Research

15–17 September 2021

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Welcome to SPhERe 2021!

Dear colleagues, partners and friends,

on behalf of the Scientific Committee and the Center of Pharmaceutical Engineering I cordially invite scientists, researchers and professionals from industry, academia and research institutions to the 4th International Symposium on Pharmaceutical Engineering Research – SPhERe – from September 15 – 17, 2021 in Braunschweig, Germany. Due to the ongoing threats by the Corona virus and the unforeseeable situation following the summer travelling season, SPhERe 2021 will take place in a completely online format.

SPhERe addresses major issues on innovative methods and processes to develop and manufacture effective and customized drugs in a cost-efficient manner. Bringing together pharmacists, process and production engineers as well as microtechnologists from academia and industry, the conference will promote multidisciplinary exchange and collaboration.

The symposium is an excellent forum specially for young scientists to share and discuss important new developments and scientific advancements in pharmaceutical engineering and related fields.

Conference contributions are especially invited addressing – but are not limited to –

  • Processes for Biological APIs
  • Processes for Chemical APIs
  • Continuous Processing
  • Solid & Liquid Preparations
  • Formulation
  • Analytics, PAT
  • Microsystems

This year‘s Hot Topic Session focuses on vaccine development & production reflecting the efforts and progresses made in developing and producing COVID-19 vaccines in a global pandemic situation.

In particular, we would like to motivate young professionals to exchange ideas with colleagues from Europe and beyond to present their results in this multidisciplinary setting. For early career scientists the conference offers the chance to get in touch with advanced researchers who will provide insight into their different career paths. The best posters will be honoured with SPhERe Poster Awards.

We are looking forward to your contributions and to welcoming you to SPhERe 2021!

Sincerely yours
Prof. Dr.-Ing. Stephan Scholl
Conference Chair

Photo by Marisol Glasserman / TU Braunschweig

Programme

Overview of the Programme, please have a look at the Programme at a Glance. 

 For the poster session please take a look at the Poster Programme

08:30   Opening & Welcome Address
             Opening of SPhERe 2021 by the Conference Chair, Stephan Scholl, TU Braunschweig, DE
             Welcome note by the TU President Angela Ittel, TU Braunschweig, DE

08:45   Keynote Lecture
             Continuous Pharmaceutical Processes: New Applications – Old Challenges. Gavin Halbert, University of Strathclyde & CMAC, GB

09:30   Bio Break
09:45   Processes for Biological APIs
             Heterologous Production of Specialized Metabolites from Dandelion Latex. B. Müller, Fraunhofer Institute for Molecular Biology                    and Applied Ecology, DE
             Selected Oral Presentations, please refer to the Programme
11:15   Bio Break

11:30   Processes for Chemical APIs and Continuous Processing
             Conventional and Flow Synthesis of Antibiotic Carbene Silver Derivatives. Matthias Tacke, University College Dublin, IE
             Selected Oral Presentations, please refer to the Programme
13:00   Lunch Break
14:00   Miscellaneous Processes
             Selected Oral Presentations, please refer to the 
Programme
15:20   Bio Break
15:30   Poster Introduction, Part I
16:00   Digital Poster Session Including Networking & Virtual Get-Together*                                                                                                                          Digital Poster Presentations, please refer to the Poster Programme                                                                                                         17:00   End of First Day

08:30   Highlight Lecture: Vaccine Development & Production
             Corona Vaccines: A Blueprint for other Vaccine Developments? Leander Grode, Vakzine Projekt Management, DE

09:15   Bio Break
09:30   Solid Preparations
             Digital Health – Digital 2D/3D Printing of Personalized Medication. Markus Dachtler, DiHeSys GmbH, DE
             Selected Oral Presentations, please refer to the 
Programme
11:00   Bio Break
11:15   Liquid Preparations
             Special Considerations on Biologics Drugs as Regards Formulation, Stability and Packaging Material Interactions.
             Karoline Bechtold-Peters, Novartis GmbH, CH
             Selected Oral Presentations, please refer to the 
Programme
12:45   Lunch Break
13:45   Formulation
             Physical Stability of Amorphous Solid Dispersions: Historical Examples and Shelf-Life Extrapolation.
             Frank Theil, Abbvie Deutschland, DE
             Selected Oral Presentations, please refer to the Programme

15:15   Bio Break

15:30   Poster Introduction, Part II
16:00   Digital Poster Session Including Networking & Virtual Get-Together*                                                                                                                          Digital Poster Presentations, please refer to the Poster Programme
17:00   End of Second Day

08:30   Career Session
             Miriam Pein-Hackelbusch, University of applied Sciences and Arts Ostwestfalen-Lippe, DE
             Ulrike Krewer, Karlsruhe Institute of Technology, DE

             Sebastian Döring, Lilian Labs GmbH, DE
10:00   Bio Break
10:15   Analytics, PAT
             In-line spectroscopic Methods as essential Part of PAT. Bernd Bleisteiner, Roland Seitz, Horiba GmbH, DE
             Selected Oral Presentations, please refer to the 
Programme
11:35   Extended Bio Break

12:00   Emerging Topic Lecture
             Towards integrated Design, Optimisation and Control in Biomanufacturing. Maria Papathanasiou, Imperial College London, GB
             Artificial Intelligence in Drug Discovery – What is Realistic, What are Illusions? Andreas Bender, NUVISAN ICB GmbH, DE
12:50   Bio Break
13:05   Microsystems
             Organ-on-Chip: Microphysiological in Vitro Models recapitulating complex Human Tissues. Peter Loskill,
             Natural and Medical Sciences Institute Tübingen, DE
             Selected Oral Presentations, please refer to the 
Programme
14:20   Remarks & Conclusions, Voting and Results of SPhERe 2021 Poster Award
14:40   End of the Conference. 

*After a short introduction the poster session is organised in breakout sessions for detailed discussion and networking. This session includes the virtual Get-Together in front of the digital posters.

Status of the scientific programme as of 14th September 2021.

Registration & Fees

Thank you for your interest in the 4th International Symposium on Pharmaceutical Engineering Research of the Center of Pharmaceutical Engineering which will be held from 15-17 September 2021.

Registration is open from June 11 to August 31, 2021. After your registration you receive a confirmation e-mail and an invoice including payment details. The log-in data of the conference will be sent after receipt of your payment approx. 1-2 days prior the conference starts.

  • Participants of research organisations  – 150 EUR plus VAT
  • Participants of industry – 225 EUR plus VAT
  • Doctoral candidates ** – 50 EUR plus VAT

* Registration fees are net amounts. According to § 3a III Nr. 5 UStG the registration fee is to be calculated with 19% VAT. For participants from abroad, the service is only affected to a limited extent by the possibility of reversing the tax liability.

**In order to obtain reduced access to the conference please send an electronic copy of your student card as a single PDF-file. Please use the online registration for submitting your student card copy.

The registration fees include conference access and the conference proceedings as PDF-file. The invoice including payment confirmation will be sent by email on short notice.

Cancellations will only be accepted in written form. In case of no-show the conference fees won’t be refunded and fees not yet paid still have to be paid. If the event is cancelled by the Center of Pharmaceutical Engineering the registration fees for the conference will be refunded. Further claims for compensation are excluded.

Call for Papers

The SPhERe conference, taking place every two years, provides a broad overview of the current science and technology of pharmaceutical engineering research. This is where scientists and engineers of various disciplines, both academic and industrial, discuss their research and exchange ideas.

The call for papers is closed now.

The conference will cover the following topics – but are not limited to –

  • Processes for Biological APIs
  • Processes for Chemical APIs
  • Continuous Processing
  • Solid & Liquid Preparations
  • Formulation
  • Analytics, PAT
  • Microsystems

We are looking forward to meeting you at the 4th International SPhERE conference 2021.

We thank all contributors for the submission of an abstract and will contact them shortly after the finalisation of the programme.

The Center of Pharmaceutical Engineering will NOT make any changes or corrective action regarding the author information, so please make sure to check them accurately.

The acceptance of the contributions will be based on the review of the abstracts by the Scientific Committee.

Please note that your abstract will only be published in the conference proceedings if you accept the Open Access Consent by signature.

Please note: Registration fee cannot be waived for presenting authors.

Abstracts of the SPhERe conference will be published in a conference volume. For open access publication the library needs the written consent of the presenting author. Your publications will be published in compliance with the applicable German copyright law, which means that the copyright remains with you. You only transfer the simple, unlimited right of use to Braunschweig University Library to reproduce, store, make the submitted publication publicly accessible on its servers. Please note that you may need to obtain the consent of co-authors for publishing. It is your responsibility to fulfill the copyright and exploitation rights of third parties.

If you are interested in open access publication you need to agree to the terms of contract for publishing in the Digital Library. Please use the Open Access Consent form and submit your signed written consent together with your abstract via the Online Abstract Submission.

Attention: Abstracts without written consent will not be published in the conference proceedings. There will be no reminders to submit your written consent by the organisers.

  • 31 July 2021: Deadline for abstract submission.
  • 20 August 2021: Confirmation of authors / Set-up of the final programme.
  • 27 August 2021: Deadline for registration of active authors.
  • 31 August 2021: Deadline for registration of participants without presentation.
  • 5 September 2021: Editorial deadline for the list of participants.
  • 5 September 2021: Deadline for submission of your final poster presentation.

Length of the oral presentations:

  • Keynote and highlight lecture: 45 minutes including discussion (35+10)
  • Emerging topic lecture: 25 minutes including discussion (20+5)
  • Invited lecture: 25 minutes including discussion (20+5)
  • Regular lecture: 15 minutes including discussion (12+3)

Strict time keeping will be essential for the smooth running of the conference.

Details on technical equipment and online settings will be sent to you in due time.

Please prepare your slides as a pptx file. In case you use special software for your presentation or if you have videos included into your file, please ask for a test run.

The poster presentation is an important facet of the scientific programme. The posters will be clustered and presented according to the final poster programme.

For posters an introductory presentation is scheduled in a separate session on day 1 and 2, followed by a dedicated poster session. Please consider that your presentation time at the poster introduction is strictly limited to one slide and two minutes each poster. Please send your poster presentation as a PDF-file no later than September 5, 2021.  Presentations received later cannot be considered in the programme.

For the poster session individual virtual meeting rooms are scheduled for the duration of the poster discussions on the first and second conference day. Further details will be provided in due time.

We highly recommend to prepare your poster in a landscape format.

There will be test sessions running several days before the SPhERe 2021 so that authors can be well prepared for the online platforms. More information about this will be sent out in due time.

In order to participate at the web conference, you will need a stable internet connection. Details on the conference tools will be provided at the end of July 2021.

Past Conferences

To get an impression of previous SPhERe conferences please screen the full programmes of the years 2015, 2017, and 2019. Open access publications of SPhERe 2019 are summarized in the conference proceedings.

Photo by Marisol Glasserman / TU Braunschweig

Conference Organisation

Venue: Digital
Date: 15 – 17 September 2021

TU Braunschweig
Center of Pharmaceutical Engineering

Prof. Dr.-Ing. Stephan Scholl

TU Braunschweig
Center of Pharmaceutical Engineering

Prof. Dr. Ludger Beerhues
Dr. Gerlinde Benninger
Prof. Dr. Heike Bunjes
Prof. Dr. Andreas Dietzel
Prof. Dr. Ing. Arno Kwade
Prof. Dr. Ing. Stephan Scholl

The conference language is English.

Technische Universität Braunschweig
Center of Pharmaceutical Engineering
SPhERe Conference Office
Franz-Liszt-Straße 35a
38106 Braunschweig, Germany

Phone: +49 (0)531 391 65502
E-Mail: pvz-sphere@tu-braunschweig.de
Web: www.pvz-sphere.de

Technische Universität Braunschweig
Zentrum für Pharmaverfahrenstechnik (PVZ)
Franz-Liszt-Str. 35a
38106 Braunschweig
Germany

Technische Universität Braunschweig is a statutory corporation. The PVZ with its SPhERe conference website is legally represented at a decentralized server by Prof. Dr.-Ing. Arno Kwade.

Controlling authority:
Ministry for Science and Culture of Lower Saxony
Leibnizufer 9
30169 Hannover
Germany
www.mwk.niedersachsen.de

EU VAT number:
DE 152330858

Responsibility under the German Press Law §55 Sect. 2 RStV
Zentrum für Pharmaverfahrenstechnik (PVZ)
Managing Director Dr. Gerlinde Benninger
Franz-Liszt-Str. 35a
38106 Braunschweig
Germany
Contact: pvz@tu-braunschweig.de

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